High miles normally is the result of many motorway miles, in that case sure a 2ltr+ oiler is a good choice
You want low end with long legs and medium speeds , then a large oiler or a V6
You want a high speed performance and long legs, then a v6 or v8
You want a town go cart or school run motor, them a small petrol
Depends on main need
My cars: Kia 998cc petrol automatic, great little thing for shopping short trips.
C5x7 Tourer, working car, motorways and large loads, comfy and relaxing 2ltrTD
Activa v6 petrol for a toy and a great GT car
Healey 3000 3ltr Petrol for brutal fun (when I fix it again) and showing off/listen to it